Office space in Philadelphia

Philadelphia commands a substantial office market across Center City and suburban rings including the Bala Cynwyd corridor and King of Prussia. The city remains a major regional financial and healthcare employment centre, anchoring the American Northeast market region.
Featured

Office spaces in Philadelphia

A selection of the best workspaces in Philadelphia

No listing found.

No listing found.

Featured

Office spaces in Philadelphia

A selection of the best workspaces in Philadelphia

Trusted by leading companies

Looking for workspace in Philadelphia?

Our advisory team searches the full market on your behalf. Cost-free service for flexible workspace searches. Shortlist within 24 hours.

market overview

Historic Northeast finance and healthcare anchor

Philadelphia anchors the Northeast regional economy with particular strength in financial services, healthcare and life sciences, insurance, and professional services. The city hosts major headquarters including Comcast, major banking operations, and significant pharmaceutical and biotech research facilities. As a regional financial centre, Philadelphia competes directly with Boston and smaller northeastern hubs rather than primary global centres, positioning it as an important secondary market for institutional investment and corporate operations.

Center City Philadelphia concentrates finance, legal, and professional services employment around the downtown core and Market Street corridor. Bala Cynwyd and the surrounding Main Line corridor have developed into mature office markets serving both Philadelphia-based companies and suburban employment clusters. King of Prussia further west provides large-format suburban office space. SEPTA rail connections link downtown to suburban job centres, whilst Philadelphia International Airport provides domestic and international connectivity. The city maintains competitive office rents relative to Boston and primary coastal markets, with substantial talent availability across finance, healthcare, and technical professions supporting ongoing corporate operations.

Key Industries

What type of companies are based in Philadelphia?

Healthcare

Life Sciences

Financial Services

Education

Pharmaceuticals

Professional Services

Your questions answered

Common questions

Center City around Market Street and Liberty Place is the main CBD, with Comcast Center, One Liberty Place and Two Liberty Place housing legal, financial services and consumer tenants including Comcast’s expanding technology campus. University City around Drexel University and the University of Pennsylvania anchors life sciences, biotech and cell and gene therapy firms including Spark Therapeutics and the Schuylkill Yards development. Navy Yard at the former naval shipyard hosts pharmaceutical headquarters including GSK and Iovance. Old City and Northern Liberties attract creative agencies, smaller tech firms and founders in converted stock. King of Prussia and Conshohocken serve suburban corporate tenants.
Philadelphia has a diverse occupier base spanning life sciences, higher education, legal services, insurance and media, anchored by Comcast, Independence Blue Cross, Penn Medicine and the Children’s Hospital of Philadelphia. The city has become the national centre for cell and gene therapy, with the University City and Navy Yard clusters absorbing significant new life sciences supply. Flex supply includes WeWork, Industrious, Regus, Benjamin’s Desk and 1776, concentrated in Center City. Demand is weighted to private suites and managed offices, with life sciences tenants increasingly taking specialised lab-enabled flex space in University City and the Navy Yard.
The concentration of cell and gene therapy, oncology and gene editing firms around Penn, CHOP and the Wistar Institute has created sustained demand for lab-enabled flex space with wet bench and BSL-2 capabilities. Operators including B+labs, IndieBio Philly and the Pennovation Center offer graduated solutions from single-bench to multi-thousand square foot private labs. These buildings require specialist ventilation, chemical handling infrastructure and shared equipment pools that general coworking cannot provide. Tenants often start in shared lab flex space in University City, then graduate to purpose-built fit-out at Schuylkill Yards or the Navy Yard as they scale toward clinical trials.
Philadelphia offers a substantial flexible workspace market dominated by serviced offices, with supply concentrated across Center City around Market Street and Penn Center, the Navy Yard innovation district, University City and the Conshohocken corporate corridor. Operators range from global brands to boutique providers serving banking, life sciences, professional services and a fast-growing tech base. Coworking is more limited but present, with operators across Center City and University City, supporting founders, scale-ups and creative agencies. Managed offices, where space is fitted bespoke for a single tenant on a flex contract, are not yet a meaningful part of the Philadelphia market.
Flexible workspace demand in Philadelphia is anchored by life sciences and pharma, with Comcast NBCUniversal’s headquarters, GSK’s US operations, Spark Therapeutics, Merck and a deep cell and gene therapy cluster (Cellicon Valley) driving substantial activity around University City and the Navy Yard. Higher education and healthcare, anchored by the University of Pennsylvania, Drexel, Jefferson Health and Children’s Hospital of Philadelphia, drive substantial demand. Financial services, including Vanguard nearby in Malvern and a deep insurance and banking community, anchor Center City. Professional services, law firms and a growing tech and fintech base round out demand.